Statistical Analysis of Variation in the Human Plasma Proteome

Figure 5

Expression data for alpha-2-HS-glycoprotein, with an average increase of 1.49-fold between the female and male groups, and FDR-adjusted gender-effect 𝑃-value =.055. The samples are in SubjectNumberTime format, where SubjectNumber ranges from 01 to 11, and the Time values {x, y, and z } correspond to {𝑇₁, 𝑇₂, and 𝑇₃}. The annotations indicate the gels (numbers) and the dyes (red for Cy5, green for Cy3) corresponding to the samples. Dotted lines connect samples multiplexed on the same gel. Crosses indicate sample averages over the technical replicates. The solid line connects all sample averages. Boxes around the three Time values for each SubjectNumber highlight male and female genders (blue and red respectively) added for illustrative purposes only.