Statistical Analysis of Variation in the Human Plasma Proteome

Table 1

Frequency distribution of the variance component estimates.

% contribution to total variance	Subject		Time in subject		Error
	(a)	(b)	(a)	(b)	(a)	(b)
0–10	6.31	6.31	63.89	63.89	6.57	6.57
10–20	9.34	15.66	17.68	81.57	17.17	23.74
20–30	12.89	28.50	7.83	89.39	16.67	40.40
30–40	14.14	42.68	4.29	93.69	9.34	49.75
40–50	13.63	56.31	2.27	95.96	10.86	60.61
50–60	11.36	67.68	3.03	98.99	11.87	72.47
60–70	11.36	79.04	0.51	99.49	10.37	82.83
70–80	11.61	90.66	0.50	100.00	8.08	90.91
80–90	7.83	98.48			4.80	95.71
90–100	1.51	100.00			4.29	100.00

The components of subject (𝜎_𝑠), time-within-subject (𝜎_𝑡), and random error (𝜎_𝑒) are shown separately as (a) the percentage of spots and (b) the cumulative percentage of spots with contribution to the total variance indicated in the first column.