Autocrine, Not Paracrine, Interferon-Gamma Gene Delivery Enhances Ex Vivo Antigen-Specific Cytotoxic T Lymphocyte Stimulation and Killing
Structure of the cell treatment protocol. Shown is the temporal treatment of the Mo/DC and T cells and is self-descriptive. However, note that AAV/IFN-γ is used to infect Mo/DC at day zero, or naive T cells just prior to coincubation with AAV/antigen-loaded DC on day 5.
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