BioMed Research International / 2010 / Article / Fig 6

Research Article

Autocrine, Not Paracrine, Interferon-Gamma Gene Delivery Enhances Ex Vivo Antigen-Specific Cytotoxic T Lymphocyte Stimulation and Killing

Figure 6

Secretion of IFN- 𝛾 from AAV-transduced cells over time. Cells were treated as indicated and secretion of IFN-γ was measured in the conditioned medium at the indicated time by ELISA. The conditions include AAV/IFN- 𝛾 delivery into DC (with concurrent AAV/CEA delivery), (a); AAV/IFN- 𝛾 delivery into T cells, (b); AAV/IFN- 𝛾 only delivery into DC, (c); cells with no treatment, (d).

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