In Vivo Bioassay of Recombinant Human Growth Hormone Synthesized in <i>B. mori</i> Pupae

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left">Group</td><td align="center"><i>n</i></td><td align="center">Liver weight ± SD (g)</td><td align="center"> Epiphyseal width ± SD (<svg height="9.6750002" id="M43" style="vertical-align:-2.29482pt" version="1.1" viewbox="0 0 9.6374998 9.6750002" width="9.6374998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,9.675)">
<g transform="translate(72,-64.26)">
<text transform="matrix(1,0,0,-1,-71.95,66.6)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝜇</tspan>
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</svg>m)</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left"> BmrhGH protein preparation<svg height="11.525" id="M44" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 6.4749999 11.525" width="6.4749999" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.525)">
<g transform="translate(72,-62.78)">
<text transform="matrix(1,0,0,-1,-71.95,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
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</svg></td><td align="center">8</td><td align="center">4.973 ± 0.1633<svg height="12.425" id="M45" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 7.9625001 12.425" width="7.9625001" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.425)">
<g transform="translate(72,-62.06)">
<text transform="matrix(1,0,0,-1,-71.95,67.11)">
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</svg></td><td align="center">44.777 ± 0.9867<svg height="12.425" id="M46" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 7.9625001 12.425" width="7.9625001" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,12.425)">
<g transform="translate(72,-62.06)">
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</svg></td></tr><tr><td align="left">Control</td><td align="center">8</td><td align="center">4.424 ± 0.0928</td><td align="center">39.453 ± 0.9216</td></tr><tr><td align="left">Blank</td><td align="center">3</td><td align="center">4.404 ± 0.0805</td><td align="center">40.200 ± 0.9473</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><svg height="11.525" id="M47" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 6.4749999 11.525" width="6.4749999" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.525)">
<g transform="translate(72,-62.78)">
<text transform="matrix(1,0,0,-1,-71.95,67.83)">
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</svg>BmrhGH protein preparation was obtained from pupae infected by vBmrhGH, and the dosage of BmrhGH was approximately 4.5 mg/rat.day. Control protein extracts were from pupae infected by WT baculovirus. Blank group was treated with 0.9% NaCl solution. “<svg height="8.7624998" id="M48" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 14.775 8.7624998" width="14.775" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,8.7625)">
<g transform="translate(72,-64.99)">
<text transform="matrix(1,0,0,-1,-71.95,65.04)">
<tspan style="font-size: 12.50px; " x="0" y="0">▵</tspan>
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</svg>” means <i>P</i>  &lt;  .05.<br/></td></tr></table>

The liver weight and epiphyseal width of hypox rats gavaged with BmrhGH (mean ± SD).

BioMed Research International

tab1

Table 1

Table 1: In Vivo Bioassay of Recombinant Human Growth Hormone Synthesized in <i>B. mori</i> Pupae 

BioMed Research International

In Vivo Bioassay of Recombinant Human Growth Hormone Synthesized in B. mori Pupae

Table 1