Genetic Immunization with CDR3-Based Fusion Vaccine Confers Protection and Long-Term Tumor-Free Survival in a Mouse Model of Lymphoma
Figure 1
DNA fusion vaccine schematic structure (a). Experimental design of protective (b) and immune responses (c) studies is showed. C3H/HeN mice were immunized twice at 3-week intervals by intramuscular injection followed by electroporation. Unimmunized (naïve) mice received a mock vaccination by injection with phosphate saline buffer. Two weeks after boosting mice were injected i.p. with cells.
