Research Article

Genetic Immunization with CDR3-Based Fusion Vaccine Confers Protection and Long-Term Tumor-Free Survival in a Mouse Model of Lymphoma

Figure 3

In vivo antitumor effects generated by immunization with pTT V H CDR3 vaccine. (a) Tumor resistance. (*) denotes a statistically significant value ( 𝑃 < . 0 0 1 ) by 𝑋 2 analysis when comparing the pTT V H CDR3 group ( 𝑛  = 7) to all other groups ( 𝑛  = 6). (b) Representative long-term tumor-free survival. Survival analyses were performed using the Kaplan-Meier method and the log-rank test ( 𝑃 = . 0 0 2 7 ).
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(a)
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(b)