Research Article

Improved Killing of Human High-Grade Glioma Cells by Combining Ionizing Radiation with Oncolytic Parvovirus H-1 Infection

Figure 5

Effects of ionizing radiation (IR) on the cell cycle of human high-grade glioma cells. Short-term cultures of human gliosarcoma NCH-37, human glioblastoma NCH-82, and human glioblastoma NCH-89 were irradiated with 10 Gy, and cell cycle analyses were performed 24 hours post-IR (a, middle column) or 48 hours post-IR (a, right column). Control cells (a, left column) were transported to the accelerator but not exposed to IR (ctrl.). (b) IR induced increase of S-Phase fraction in percent of unirradiated control cells.