Research Article

Improved Killing of Human High-Grade Glioma Cells by Combining Ionizing Radiation with Oncolytic Parvovirus H-1 Infection

Table 2

Titer of infectious virus particles in the supernatant of irradiated (10 Gy) or nonirradiated (0 Gy) human high-grade glioma cell lines 1 hour and 3 days post H-1PV infection.

1 hour p.i.3 days p.i.

NCH-3710 Gy1: 1001: 10,000
0 Gy1: 101: 1,000

NCH-8210 Gy1: 1001: 10,000
0 Gy1: 1001: 10,000

NCH-8910 Gy1: 1001: 10,000
0 Gy1: 1001: 10,000

NCH-307in vivo*1: 101: 1,000

*in vivo irradiated recurrent glioblastoma cell line NCH-307 was not irradiated in vitro.