Trisomy 14 as a Sole Chromosome Abnormality Is Associated with Older Age, a Heterogenous Group of Myeloid Neoplasms with Dysplasia, and a Wide Spectrum of Disease Progression

Table 2

Clinical, morphologic, and cytogenetic characteristics of patients with myelodysplastic/myeloproliferative neoplasms and isolated trisomy 14.

Age (Y)	Sex	WBC (10^9/L)	Hb (g/dL)	Platelet (10^9/L)	WHO classification	Karyotype	Cellularity (%)	Blast (%)	Trilineage dysplasia	IPSS score
68	M	14.8	13.7	626	CMML-1	47, XY, +14 [16]	85	8	Yes	1.0
72	M	18.6	8.8	198	CMML-1	47, XY, +14 [16]	90	2	Yes	0.5
86	F	11.3	10.8	171	CMML-1	47, XX, +14 [16]	95	9	Yes	1.0
51	F	7.6	12.3	160	CMML-2	46, XX, i(14)(q10) [16]	35	17	Yes	2.0
77	F	19.2	9.7	291	MDS/MPN-U	47, XX, +14 [14]/46, XX [3]*	100	6	Yes	1.0

*Unknown karyotype at time of initial diagnosis.
Y: years; M: male; F: female; WBC: white blood cell; Hb: hemoglobin; CMML: chronic myelomonocytic leukemia; MDS/MPN-U: myelodysplastic/myeloproliferative neoplasm, unclassifiable; IPSS: international prognostic scoring system.