Trisomy 14 as a Sole Chromosome Abnormality Is Associated with Older Age, a Heterogenous Group of Myeloid Neoplasms with Dysplasia, and a Wide Spectrum of Disease Progression

Table 3

Clinical, morphologic, and cytogenetic characteristics of patients with acute myeloid leukemia and isolated trisomy 14.

Age (Y)	Sex	WBC (10^9/L)	Hb (g/dL)	Platelet (10^9/L)	WHO classification	Karyotype	Cellularity (%)	Blast (%)	Trilineage dysplasia
70	M	4.3	10.3	56	AML with maturation	47, XY, i(14)(q10) [2]/46, XY [17]*	55	26	Yes
61	M	162	8.1	63	AML with maturation	47, XY, +14 [16]	95	60	Yes
57	M	1.1	9.7	59	AML without maturation	47, XY, +14 [2]/46, XY [17]*	25	50	Yes
65	M	2.1	10.1	305	AML with maturation	47, XY, +14 [16]	85	37	Yes

*Abnormal clone confirmed by FISH.
Y: years; M: male; F: female; WBC: white blood cell; Hb: hemoglobin.