Trisomy 14 as a Sole Chromosome Abnormality Is Associated with Older Age, a Heterogenous Group of Myeloid Neoplasms with Dysplasia, and a Wide Spectrum of Disease Progression

Table 5

Median survival and disease progression in patients with isolated trisomy 14.

Features	MDS (𝑛=7)	MDS/MPN (𝑛=5)	AML (𝑛=4)
Median survival (range) (month)	28 (10.5–75)	31.5 (31–32)	9 (2–12)
Leukemic transformation	43%	20%	N/A
Median interval of disease progression (month)	7.75	29	N/A

MDS: myelodysplastic syndrome; MDS/MPN: myelodysplastic/myeloproliferative neoplasms; AML: acute myeloid leukemia; N/A: not applicable.