Computational Method for Estimating DNA Copy Numbers in Normal Samples, Cancer Cell Lines, and Solid Tumors Using Array Comparative Genomic Hybridization

Figure 3

(a) Signal intensity of SNPs (𝑦 axis) for ovarian cancer cell line OVCAR8 before adjustment on genome size. (b) Fraction of SNPs (𝑥 axis) with a certain signal intensity (𝑦 axis) for ovarian cancer cell line OVCAR8 (see (a)). (c) CN solution for ovarian cancer cell line OVCAR8 after adjustment on genome size (𝑘=1.167).

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