Research Article

Computational Method for Estimating DNA Copy Numbers in Normal Samples, Cancer Cell Lines, and Solid Tumors Using Array Comparative Genomic Hybridization

Table 3

Frequent homozygous deletions observed in 178 cancer cell lines. Chromosomal positions are based on March 2006 version of the UCSC Human Genome Browser.

RegionNumber of observationLikely tumor suppressor gene

chr2:141238933-1418348217LRP1B
chr3:59686057-6119584929FHIT
chr4:91615328-922726056
chr6:162091010-1626976955PARK2
chr7:38238069-383714966
chr7:141707985-1422105945
chr9:19866496-2855013036CDKN2A (p16), CDKN2B
chr10:88921717-911641556PTEN
chr14:21159134-220673647
chr16:6161277-71019499
chr16:76814181-7777368926WWOX
chr20:14275899-1535242522