Association of Combined Maternal-Fetal TNF-𝛼 Gene G308A Genotypes with Preterm Delivery: A Gene-Gene Interaction Study

Table 3

LRTs for maternal and fetal genotype effects and their interaction.

Model^#	TNF-𝛼 G308A
	Log-likelihood*	P value**
I	−728.3	—
II	−724.8	.030^†
III	−723.0	.005^†
IV	−722.0	.013^†
V	−719.4	.023^§

^#: Model I: with mating-type only; model II: with mating-type plus fetal genotype; model III: with mating-type plus maternal genotype; model IV: with mating-type plus fetal genotype and maternal genotype; model V: with mating-type plus combined maternal-fetal genotype.
*: The log-likelihoods were estimated using the LEM software.
**: LRTs, for a χ ² distribution with df equal to the difference in the number of parameters being fitted.
^†: Compared with Model I.
^§: Compared with Model IV.