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Journal of Biomedicine and Biotechnology
Volume 2010 (2010), Article ID 396847, 9 pages
Research Article

MHC I Stabilizing Potential of Computer-Designed Octapeptides

1Institute of Organic Chemistry and Chemical Biology, Johann Wolfgang Goethe-Universität, Siesmayerstraße. 70, 60323 Frankfurt am Main, Germany
2Clinical Research Group Tumor Immunologie, Skin Cancer Center Charité, Clinic of Dermatology, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany
3Institut für Organische Chemie, Universität Tübingen, Auf der Morgenstelle 18, 74076 Tübingen, Germany
4Institute of Molecular Biology and Bioinformatics, Charité-Universitätsmedizin Berlin, Arnimallee 22, 14195 Berlin, Germany
5Institute of Pharmaceutical Sciences, ETH Zürich, Wolfgang-Pauli-Street. 10, 8093 Zürich, Switzerland

Received 28 September 2009; Revised 27 January 2010; Accepted 8 March 2010

Academic Editor: Yongqun Oliver He

Copyright © 2010 Joanna M. Wisniewska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary 1: a descriptor list with specifications of the descriptors used for encoding each residue of an octapeptide.

Supplemantary 2: experimental results of 180 tested octapeptides including experimental EC50 value, computed SYFPEITHI score and IEDB-ANN score of the octapeptides.

  1. Supplementary Material