BioMed Research International / 2010 / Article / Fig 1

Letter to the Editor

Exploring the 7p22.1 Chromosome as a Candidate Region for Autism

Figure 1

Physical mapping of the breakpoint on chromosome 7. (a) Dual color painting using directly FITC labelled (green) chromosome 7 paint and Rhodamine labelled (red) chromosome 16 paint. Both derivatives 7 and 16 (arrow) show clear evidence of a reciprocal exchange of chromatin from distal 7p and distal 16p, respectively. (b) Physical map of the genomic region 7p22.1 derived from the October 2009 version of the UCSC Genome Browser ( The genomic clones covering the region flanking the translocation breakpoint are indicated by black lines (S: spanning, NT: non-translocated). The breakpoint (Bp) region is represented by an arrow. The genomic location of candidate genes is represented by rectangles.

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