Research Article

Expression of Monocarboxylate Transporters 1, 2, and 4 in Human Tumours and Their Association with CD147 and CD44

Table 1

Frequency of MCTs, CD147, and CD44 expressions in tumour samples.

Tumour typeExpression
MCT1MCT2MCT4CD147CD44
Positive (%)Positive (%)Positive (%)Positive (%)Positive (%)
𝑛 CytaPM 𝑛 CytaPM 𝑛 CytaPM 𝑛 Cyta/PM 𝑛 Cyta/PM

Breast carcinoma2221 (95.5)5 (22.7)2434 (100.0)0 (0.0)2419 (79.2)1 (4.2)2813 (46.4)278 (29.6)
Colon adenocarcinoma3223 (71.9)19 (59.4)2929 (100.0)0 (0.0)2619 (73.1)0 (0.0)3413 (38.2)314 (12.9)
Nonsmall cell lung cancer2314 (60.9)5 (21.7)2121 (100.0)0 (0.0)2316 (69.6)0 (0.0)2813 (46.4)2712 (44.4)
Ovarian adenocarcinoma2418 (75.0)10 (41.7)3018 (93.3)0 (0.0)2813 (46.4)1 (3.6)2611 (42.3)282 (7.1)

Cyt: cytoplasm; PM: plasma membrane; awith or without plasma membrane staining.
Note: for CD147 and CD44, frequency results are the same for cytoplasm and plasma membrane expression.