Research Article

Expression of Monocarboxylate Transporters 1, 2, and 4 in Human Tumours and Their Association with CD147 and CD44

Table 4

Correlations between MCTs and CD44 expressions in tumours.

CD44 expression

BreastColonLungOvary
š‘› Positive (%) š‘ƒ š‘› Positive (%) š‘ƒ š‘› Positive (%) š‘ƒ š‘› Positive (%) š‘ƒ

MCT1Cytoplasma.364.2181.250
ā€ƒNegative11 (100.0)62 (33.3)93 (33.3)51 (20.0)
ā€ƒPositive217 (33.3)202 (10.0)135 (38.5)150 (0.0)
Plasma membrane.309.591.0391
ā€ƒNegative175 (29.4)92 (22.2)174 (23.5)101 (10.0)
ā€ƒPositive53 (60.0)172 (11.8)54 (80.0)100 (0.0)

MCT4Cytoplasma1.539.613.482
ā€ƒNegative41 (25.0)51 (20.0)61 (16.7)132 (15.4)
ā€ƒPositive186 (33.3)182 (11.1)156 (40.0)110 (0.0)
Plasma membrane.318ā€”ā€”1
ā€ƒNegative216 (28.6)233 (13.0)217 (33.3)232 (8.7)
ā€ƒPositive11 (100.0)0ā€”0ā€”10 (0.0)

awith or without plasma membrane staining.