Cytokine-Induced NK-Like T Cells: From Bench to Bedside

Figure 1

Marrow cells obtained from newly diagnosed AML samples analyzed by side scatter versus CD45 staining show a large proportion of leukemic blasts that are CD45dim and a much smaller fraction of normal lymphocytes that are CD45bright (a). Culture of the bulk marrow cells comprising of majority of leukemic blasts with a small fraction of lymphocytes under CIK condition (b) is able to generate an end product comprising of a majority of CD3⁺ cells with a variable CD3⁺CD56⁺ fraction (c).