Review Article
Cytokine-Induced NK-Like T Cells: From Bench to Bedside
Table 1
Comparison of the three subsets of cells in a CIK culture. NA = not applicable, ND = not done.
| Subset | Name | Cytotoxicity | Target class I | Immunophenotype | versus | versus | versus | Blocked | Enhanced | %CD8 | Memory T cell subset | Granzyme | AML | ALL | K562 | content |
| CD3−D56+ | NK cells | + | 0 | ++++ | Killing | Killing | NA | NA | ND | CD3+CD56+ | NK-like T cells | +++ | 0 | 0 | Killing | Killing | higher | CD27+/−CD28−CD62L+ late T effector | higher | CD3+CD56− | T cells | + | 0 | 0 | Killing | Killing | lower | CD27+CD28+CD62L+ early T effector | lower |
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