Research Article

The Unexpected Role for the Aryl Hydrocarbon Receptor on Susceptibility to Experimental Toxoplasmosis

Figure 3

Levels of IL-12p70 (a), IFN- 𝛾 (b), TNF- 𝛼 (c), IL-10 (d) nitric oxide (e), and total IgE (f) in sera from AhR-/- and WT mice infected with 40 cysts of T. gondii. For systemic cytokine, nitric oxide, and IgE production, mice were bled at the indicated time points and the levels of cytokines and total IgE (f) were measured in serum by ELISA and nitric oxide (e) was measured in serum by Griess assay as described above. The values presented are the mean + SD of triplicate samples of 6 animals per time point per group. 𝑃 < . 0 5 with respect to WT, Student’s t-test.
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