Research Article

Cytokine-Induced Monocyte Characteristics in SLE

Figure 3

The distribution of H4ac at the promoter. (a) H4ac was distributed around the transcription start site. (b) The SLE monocytes had increased H4ac globally around the transcription start site. (c) The average of H4ac at potential TFBSs (grey area) was different from the general pattern of H4ac around TSS (black line), most notably, it was higher in the promoter region, but lower immediately after the TSSs. (d). In SLE, the average change of H4ac at potential TFBS (grey area) was also different from the general pattern (black line).
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(a)
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(b)
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(c)
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(d)