Reduced Expression of TCR Zeta Is Involved in the Abnormal Production of Cytokines by Peripheral T Cells of Patients with Systemic Lupus Erythematosus
Figure 3
Correlation between the expression levels of TCR zeta and cytokines. The amounts of TCR zeta expressed in control and SLE T cells were estimated as described in Materials and Methods. The amount of TCR zeta in T cells from individual patient was normalized against the average of the control. (a) The average expression level of TCR zeta of SLE T cells was compared with that of control T cells. Data represent mean SD. (b, c) Scattergrams were depicted between the expression level of TCR zeta and the expression level of IFN- (b) or IL-2 (c).
