Research Article
The Differential Expression of Aqueous Soluble Proteins in Breast Normal and Cancerous Tissues in Relation to Stage and Grade of Patients
Table 2
Identity and properties of twenty-four differentially expressed proteins.
| Protein spot no. | SwissProt Accession Number | Protein name | Molecular class | Molecular weight (Da) | Isoelectric point (pI) | GRAVY score | MOWSE score | Sequence coverage (%) |
| 1 | P02768 | Serum albumin precursor | Transport/cargo | 71397 | 5.92 | | 96 | 14 | 2 | P00441 | Superoxide dismutase | Oxidoreductase | 16168 | 5.70 | | 52 | 9 | 3 | P32119 | Peroxiredoxin-2 | Oxidoreductase | 21935 | 5.67 | | 260 | 26 | 4 | P00739 | Haptoglobin-related precursor | Transport/cargo | 39529 | 6.42 | | 43 | 3 | 5 | P02766 | Transthyretin precursor | Transport/cargo | 16003 | 5.52 | | 75 | 22 | 6 | P15090 | Fatty acid binding protein | Carrier protein | 14704 | 6.81 | | 223 | 24 | 7 | P00738 | Haptoglobin precursor, allele 2 (validated) | Transport/cargo | 45901 | 6.13 | | 56 | 6 | 8 | P02768 | Serum albumin precursor (validated) | Transport/cargo | 69366 | 5.92 | | 46 | 4 | 9 | P00739 | Haptoglobin- related protein precursor | Transport/cargo | 39529 | 6.42 | | 55 | 3 | 10 | P09211 | Glutathione transferase | Transferase | 23464 | 5.42 | | 277 | 53 | 11 | P68371 | Class IV beta tubulin | Structural protein | 50217 | 4.82 | | 52 | 13 | 12 | P55735 | SEC13-like 1, isoform b | Transport/cargo | 36062 | 5.22 | | 115 | 37 | 13 | P02675 | Fibrinogen beta chain precursor | Coagulation factor | 56624 | 8.54 | | 87 | 28 | 14 | P02675 | Fibrinogen beta chain precursor | Coagulation factor | 56624 | 8.54 | | 134 | 31 | 15 | P27797 | Calreticulin | Calcium binding protein | 47092 | 4.30 | | 107 | 29 | 16 | Not available | Unidentified protein | N/A | N/ | N/A | N/A | N/A | N/A | 17 | Q63610 | Hypothetical protein | Hypothetical protein | 27407 | 4.71 | | 59 | 27 | 18 | P63104 | 14-3-3 protein zeta (kinase regulator) | Adaptor molecule | 27745 | 4.73 | | 193 | 47 | 19 | Q04917 | 14-3-3 protein eta | Adaptor molecule | 28244 | 4.76 | | 71 | 23 | 20 | P52907 | F-actin capping protein | Cytoskeletal protein | 32965 | 5.45 | | 53 | 26 | 21 | P02766 | Transthyretin precursor | Transport/cargo | 16003 | 5.52 | | 85 | 22 | 22 | P68133 | Actin alpha | Cytoskeletal protein | 38172 | 5.39 | | 64 | 17 | 23 | P07195 | L-lactate dehydrogenase | Dehydrogenase | 36928 | 5.71 | 0.056 | 222 | 34 | 24 | P21695 | Glycerol-3-phosphate dehydrogenase | Dehydrogenase | 38206 | 5.81 | 0.106 | 312 | 51 |
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