Research Article

The Vacuolar-Type -ATPase in Ovine Rumen Epithelium is Regulated by Metabolic Signals

Figure 1

Results of dose-response experiments with antimycin A and/or 2-DOG. The p H i of ruminal epithelial cells was measured in either HEPES-buffered H C O 3 -free Na-medium containing 5 mM glucose (control) or in glucose-free media with blockers as indicated. The mean p H i reduction from the p H i measured in control medium with glucose is given. Values are means ± SE from 3 single measurements; a 𝑃 < . 0 5 versus the lowest dosage used.