Research Article

The Adenovirus Type 3 Dodecahedron's RGD Loop Comprises an HSPG Binding Site That Influences Integrin Binding

Figure 2

Mutations in the Bs-Dd RGD loop. (a) Sequence of Bs-Dd mutants in either the RGD or the basic motif (blue boxes). Mutations are indicated in red. (b) Detection of baculovirus expressed protein by western-blot using an anti-dodecahedron serum. (c) Negative staining micrographs of purified mutants and wild type Bs-Dd showing that dodecamerisation is not affected by the mutations.