Research Article

iTRAQ Quantitative Analysis of Multidrug Resistance Mechanisms in Human Gastric Cancer Cells

Figure 4

The effect of enforced expression of MVP on drug resistance in SGC7901 cells. (a) Western blot analysis showed that two stable clones with overexpression of ectopic MVP were generated. Subsequently, MTT assay showed that overexpression of ectopic MVP could result in vincristine and adriamycin resistance, with the significant increase of the cell viability (b). The experiment was repeated in triplicate. Points: mean viable cells (% of control) from three experiments; bars: SE *: 𝑃 . 0 5 differ from control by t-test.
571343.fig.004a
(a)
571343.fig.004b
(b)
571343.fig.004c
(c)