Research Article

Production of Newcastle Disease Virus by Vero Cells Grown on Cytodex 1 Microcarriers in a 2-Litre Stirred Tank Bioreactor

Table 3

NDV Production result (HA and TCID50).

RunCell inoculums (cells/mL) ( 𝐴 )Serum conc. (%) ( 𝐵 )MOI ( 𝐶 )Max. HA titer (HAU/mL)Max. infectivity titer (tcid50/mL)

1 1 . 0 × 1 0 5 0.5210240 4 . 7 9 × 1 0 7
2 0 . 5 × 1 0 5 2210240 4 . 6 7 × 1 0 7
3 1 . 0 × 1 0 5 20.21280 3 . 2 2 × 1 0 7
4 0 . 5 × 1 0 5 0.50.2640 3 . 0 8 × 1 0 7