Intranasal Immunization with Chitosan/pCAGGS-flaA Nanoparticles Inhibits Campylobacter jejuni in a White Leghorn Model

Table 1

Immunogenicity assay of C. jejuni chitosan-DNA vaccine in chickens.

Group	Titers of antibodies in serum		Titers of antibodies in intestinal mucosa
	Second immunization	Third immunization	Second immunization	Third immunization
CS-pCAGGS-flaA	96.0±55.4^a	426.7±147.8^a	65.3±62.0^b	170.7±73.9^a
CS-pCAGGS	26.7±9.2	23.3±18.5	34.7±28.1	13.3±4.6
PBS	26.7±9.2	23.3±18.5	34.7±28.1	29.3±30.3

aHigh significantly different (𝑃<.01) among vaccine groups as calculated by Student’s 𝑡-test.
bSignificantly different (𝑃<.05) among vaccine groups as calculated by Student’s 𝑡-test.
“CS” is the short form for chitosan.