Research Article

Intranasal Immunization with Chitosan/pCAGGS-flaA Nanoparticles Inhibits Campylobacter jejuni in a White Leghorn Model

Table 4

The number of C. jejuni in small intestine, large intestine, and cecum after oral challenge.

OrganGroupCFU (CFU/g)
3 days6 days9 days12 days15 days18 days21 days

Small intestine1 9 . 2 × 1 0 3 3 . 4 × 1 0 3 6 . 0 × 1 0 2 8 . 2 × 1 0 3 1 . 9 × 1 0 3 0 0
2 3 . 5 × 1 0 2 7 . 6 × 1 0 2 1 . 2 × 1 0 2 1 . 4 × 1 0 4 5 . 9 × 1 0 4 6 . 3 × 1 0 3 7 . 6 × 1 0 4
3 2 . 0 × 1 0 3 6 . 3 × 1 0 2 7 . 3 × 1 0 2 1 . 7 × 1 0 3 1 . 2 × 1 0 5 2 . 9 × 1 0 4 3 . 8 × 1 0 4
Large intestine1 4 . 6 × 1 0 5 1 . 1 × 1 0 6 1 . 5 × 1 0 7 4 . 8 × 1 0 6 2 . 9 × 1 0 6 3 . 5 × 1 0 6 6 . 5 × 1 0 5
2 5 . 4 × 1 0 7 3 . 2 × 1 0 7 2 . 2 × 1 0 7 1 . 1 × 1 0 7 1 . 8 × 1 0 8 4 . 2 × 1 0 7 1 . 5 × 1 0 8
3 4 . 7 × 1 0 7 2 . 1 × 1 0 7 2 . 2 × 1 0 7 9 . 3 × 1 0 7 3 . 5 × 1 0 8 3 . 2 × 1 0 7 1 . 8 × 1 0 7
Cecum1 2 . 2 × 1 0 6 4 . 5 × 1 0 6 2 . 8 × 1 0 7 2 . 9 × 1 0 7 3 . 7 × 1 0 7 3 . 0 × 1 0 7 1 . 2 × 1 0 7
2 2 . 7 × 1 0 8 1 . 8 × 1 0 8 7 . 4 × 1 0 8 2 . 4 × 1 0 8 1 . 9 × 1 0 8 2 . 6 × 1 0 9 2 . 3 × 1 0 9
3 4 . 3 × 1 0 8 2 . 2 × 1 0 8 4 . 0 × 1 0 8 4 . 0 × 1 0 8 2 . 6 × 1 0 8 4 . 7 × 1 0 9 2 . 7 × 1 0 9

Group 1: CS-pCAGGS-flaA group.
Group 2: CS-pCAGGS group.
Group 3: PBS group.