Research Article

Antinociceptive and Toxicological Effects of Dioclea grandiflora Seed Pod in Mice

Table 1

Effect of EDgP on acetic acid-induced writhings in mice.

TreatmentDose (mg/kg, i.p.)Number of writhingsInhibition (%)

Control (10 mL/kg, i.p.)22.3 ± 3.1
D. grandiflora 75 1.8 ± 1.4*91.9
150 2.8 ± 2.2*87.4
300 0.5 ± 0.5*97.8
Morphine 6 1.2 ± 1.2*94.6

Values are mean ± S.E.M. ( 𝑛 = 1 0 ) . 𝑃 < . 0 0 1 versus control, Bonferroni test.