Research Article

Oral Microencapsulated Live Saccharomyces cerevisiae Cells for Use in Renal Failure Uremia: Preparation and In Vivo Analysis

Table 2

Effect of APA microcapsules on selected microbes in the human large intestine.

MicrobesIncubation time [hr]Log CFU/ml medium
Normal-TPUremic-empty APA microcapsulesUremic-TP

Total aerobes0 8 . 2 2 ± 0 . 1 2 8 . 2 2 ± 0 . 1 1 8 . 2 2 ± 0 . 0 9
6 8 . 2 7 ± 0 . 0 1 8 . 1 7 ± 0 . 1 6 8 . 2 6 ± 0 . 0 8
12 8 . 2 4 ± 0 . 1 4 8 . 3 4 ± 0 . 0 4 8 . 3 1 ± 0 . 0 7
24 8 . 2 9 ± 0 . 1 8 . 3 2 ± 0 . 0 2 8 . 2 8 ± 0 . 0 3

Total anaerobes0 8 . 3 7 ± 0 . 0 3 8 . 3 7 ± 0 . 0 1 8 . 3 7 ± 0 . 0 1
6 8 . 3 5 ± 0 . 0 9 8 . 3 9 ± 0 . 0 2 8 . 3 1 ± 0 . 1
12 8 . 3 8 ± 0 . 1 1 8 . 4 1 ± 0 . 0 7 8 . 3 8 ± 0 . 1 2
24 8 . 3 7 ± 0 . 1 4 8 . 4 ± 0 . 1 1 8 . 3 6 ± 0 . 1 6

Escherichia coli0 8 . 2 9 ± 0 . 1 3 8 . 2 9 ± 0 . 0 8 8 . 2 9 ± 0 . 1 1
6 8 . 2 4 ± 0 . 1 6 8 . 3 3 ± 0 . 0 5 8 . 2 9 ± 0 . 1 2
12 8 . 2 7 ± 0 . 1 1 8 . 2 4 ± 0 . 1 7 8 . 3 2 ± 0 . 1
24 8 . 3 1 ± 0 . 0 7 8 . 2 8 ± 0 . 1 2 8 . 2 7 ± 0 . 1 1

Staphylococcus sp.0 6 . 6 5 ± 0 . 1 4 6 . 6 5 ± 0 . 1 2 6 . 6 5 ± 0 . 1
6 6 . 7 4 ± 0 . 0 7 6 . 5 7 ± 0 . 1 6 6 . 7 2 ± 0 . 0 3
12 6 . 5 9 ± 0 . 1 5 6 . 6 1 ± 0 . 0 6 6 . 6 9 ± 0 . 0 1
24 6 . 6 4 ± 0 . 1 3 6 . 6 2 ± 0 . 1 2 6 . 5 8 ± 0 . 0 8
48 6 . 7 1 ± 0 . 0 7 6 . 7 4 ± 0 . 1 2 6 . 6 ± 0 . 1 7

Lactobacillus sp.0 5 . 3 2 ± 0 . 0 1 5 . 3 2 ± 0 . 0 6 5 . 3 2 ± 0 . 0 3
6 5 . 4 ± 0 . 0 5 5 . 4 1 ± 0 . 0 1 5 . 3 6 ± 0 . 0 8
12 5 . 4 5 ± 0 . 0 3 5 . 3 9 ± 0 . 0 5 5 . 3 3 ± 0 . 1 1
24 5 . 3 9 ± 0 . 0 9 5 . 3 7 ± 0 . 1 2 5 . 3 7 ± 0 . 1 1
48 5 . 3 6 ± 0 . 1 5 . 3 5 ± 0 . 0 8 5 . 4 1 ± 0 . 0 1
72 5 . 3 8 ± 0 . 1 7 5 . 4 2 ± 0 . 1 2 5 . 4 5 ± 0 . 1 5