Biomarkers that correlate with histological findings in lupus nephritis.
|Authors, year||Biomarkers studied||Main findings|
|Oates et al., 2008 ||Serum nitrate and nitrite levels||Serum nitrate plus nitrite levels associated with SLE disease activity score; higher nitrate/nitrite levels associated with histological proliferative renal lesions|
|Marks et al., 2008 ||Glomerular MCP-1 expression||Glomerular monocyte chemoattractant protein-1 (MCP-1) expression higher in class III and class IV than other classes of lupus nephritis|
|Nakayamada et al., 2007 ||1-integrin (CD29) expression on T cells||CD29 expression on T cells upregulated in active SLE, especially in active diffuse proliferative lupus nephritis|
|Avihingsanon et al., 2006 ||Chemokine and growth factor mRNA levels in urinary sediments||Urine interferon-producing protein 10 (IP-10), CXCR3, TGF-, and VEGF mRNA levels associated with class IV lupus nephritis|
|do Nascimento et al., 2006 ||Antiribosomal P antibody||Frequency of antiribosomal P antibody higher in class V than other classes of lupus nephritis|
|Oates et al., 2005 ||Urine glycoprotein panel||An urinary glycoprotein panel may help to differentiate different histological classes of lupus nephritis|