The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus

Table 3

Additive model association results from IFNK locus in each ancestral background.

SNP	MA	European				African-Americans				Asians
		Case	Cont	OR	𝑃	Case	Cont	OR	𝑃	Case	Cont	OR	𝑃
rs10967964	A	0.112	0.111	1.01	.88	0.022	0.025	0.85	.52	0.201	0.219	0.95	.50
rs1838430	C	0.037	0.042	0.87	.16	0.319	0.299	1.09	.27	—	—	—	—
rs1977661	A	0.099	0.114	0.85	.010	0.136	0.124	1.13	.29	0.307	0.318	0.99	.88
rs10812605	G	0.352	0.351	1.00	.93	0.411	0.393	1.08	.32	0.395	0.402	0.95	.50
rs12553951	C	0.077	0.068	1.15	.06	0.016	0.009	1.79	.09	—	—	—	—
rs4609281	C	0.277	0.282	0.98	.57	0.483	0.462	1.09	.25	0.237	0.200	1.17	.06
rs11792285	A	0.376	0.365	1.05	.24	0.098	0.100	0.98	.89	0.287	0.295	0.98	.76
rs13290599	A	0.069	0.066	1.05	.54	0.056	0.056	1.01	.93	0.118	0.138	0.85	.10
rs4879541	A	0.488	0.486	1.01	.87	0.165	0.166	1.01	.94	0.354	0.331	1.05	.50
rs2814707	A	0.237	0.232	1.03	.54	0.196	0.233	0.80	.014	0.059	0.043	1.27	.13
rs7469146	A	0.490	0.488	1.01	.83	0.120	0.126	0.96	.71	0.357	0.339	1.03	.73
rs10812611	G	0.466	0.466	1.00	.97	0.127	0.134	0.95	.64	0.357	0.337	1.03	.65
rs3861016	C	0.066	0.076	0.85	.038	—	—	—	—	0.156	0.147	1.09	.39
rs17769217	C	0.127	0.128	0.99	.93	0.041	0.031	1.32	.18	—	—	—	—
rs10967977	G	0.201	0.190	1.07	.15	0.028	0.037	0.77	.22	0.193	0.202	0.97	.76
rs13691	A	0.268	0.258	1.05	.27	0.079	0.080	1.02	.89	0.445	0.435	1.00	.98
rs12349820	G	0.236	0.232	1.02	.64	0.137	0.147	0.91	.40	0.109	0.096	1.09	.44
rs12686452	G	0.243	0.246	0.98	.61	0.138	0.126	1.12	.30	0.272	0.284	0.94	.42

MA: minor allele, “Case” and “Cont”: allele frequency of the minor allele in cases and controls, respectively, OR: odds ratio, 𝑃 = 𝑃 value.