A Comprehensive In Silico Analysis of the Functional and Structural Impact of SNPs in the IGF1R Gene

Figure 2

(a) Native structure (2jo9) showing arginine at position 1216. (b) Mutant modeled structure (2jo9 R1216C) showing cysteine residue at position 1216. (c) Superimposed structure of native structure (2jo9) (green) with mutant modeled structure (2jo9 R1216C) (gray).

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(b)

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