A Novel Lectin with Antiproliferative and HIV-1 Reverse Transcriptase Inhibitory Activities from Dried Fruiting Bodies of the Monkey Head Mushroom Hericium erinaceum

Figure 5

Mitogenic response of murine splenocytes to the lectin isolated from H. erinaceum as reflected by uptake of [methyl-³H] thymidine uptake in vitro. Results represent means ± SD (𝑛=3). Maximal stimulation of thymidine uptake was brought about by a lectin concentration of 20 𝜇M. There was an approximately 36-fold increase over the control value without lectin. Different alphabets next to the data points indicate statistically significant difference (𝑃<.05) when the data are analyzed by analysis of variance followed by Duncan’s multiple range test.