A Novel Lectin with Antiproliferative and HIV-1 Reverse Transcriptase Inhibitory Activities from Dried Fruiting Bodies of the Monkey Head Mushroom Hericium erinaceum
Table 1
Summary of purification of HEA (from 20 g dried fruit bodies).
Total
Specific
Recovery
Chromatographic
Yield
Hemagglutinating
hemagglutinating
hemagglutinating
fraction
(mg/20 g)
Activity
Activity
Activity
(
(U/mg)
(%)
Crude Extract
11840
3.6
30.64
100
Ammonium
sulfate
989.6
5.12
517
8.358
precipitate
D1
149.71
—
—
—
D2
67.5
—
—
—
D3
175.058
1.66
950
1.4
D4
759.75
1.6
2.1
6.4
C1
50.754
—
—
—
C2
27.516
0.544
1978
0.23
C3
45.528
—
—
—
C4
20.985
—
—
—
Q1
0.6044
—
—
—
Q2
8.3924
—
—
—
Q3
13.34
0.512
3838
0.11
SU1
10.35
0.5
4830
0.087
SU2
3.04
—
—
—
The lectin-enriched fractions and the associated data are highlighted in boldface.