Aberrant Methylation of Thrombospondin-1 and Its Association with Reduced Expression in Gastric Cardia Adenocarcinoma

<table>Methylation analysis of TSP1 in tumor tissue (T) and corresponding normal tissue (N). u: indicates the presence of unmethylated genes; m: indicates the presence of methylated genes; M: 100 bp DNA marker. Case <svg height="10.6875" id="M72" style="vertical-align:-0.0pt" version="1.1" viewbox="0 0 7.9375 10.6875" width="7.9375" xmlns="http://www.w3.org/2000/svg">
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</svg>: the tumor is fully methylated, whereas the corresponding normal tissue has a very faint band demonstrating methylation; Case 2: tumor-specific methylation; Case 3: both of tumor and corresponding normal tissues are unmethylated.</table>

BioMed Research International

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Figure 1

Figure 1: Aberrant Methylation of Thrombospondin-1 and Its Association with Reduced Expression in Gastric Cardia Adenocarcinoma 