Impaired Skeletal Muscle Repair after Ischemia-Reperfusion Injury in Mice

<table>Muscle weights after ischemia-reperfusion injury and myotoxic injury. Values are means ± SEM. Number of data per group is 4–6.  IR+: ischaemic/reperfused muscles, IR−: control muscles of ischaemic/reperfused muscles, M+: myotoxin-treated muscles, M−: control muscles of myotoxin-treated muscles-do not you-mean contralateral muscle of myotoxin-treated mice?. (a) significantly different from control (<svg height="11.25" id="M25" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 48.337502 11.25" width="48.337502" xmlns="http://www.w3.org/2000/svg">
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<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="26.056252" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">5</tspan>
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</svg>), (b) significantly different from 28 days (<svg height="11.25" id="M26" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 48.337502 11.25" width="48.337502" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.25)">
<g transform="translate(72,-63)">
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<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="26.056252" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">5</tspan>
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</svg>), (c) significantly different from 56 days (<svg height="11.25" id="M27" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 48.337502 11.25" width="48.337502" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,11.25)">
<g transform="translate(72,-63)">
<text transform="matrix(1,0,0,-1,-71.95,63.35)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="26.056252" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">5</tspan>
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</svg>), (d) significantly different from M+.</table>

BioMed Research International

fig5

Figure 5

Figure 5: Impaired Skeletal Muscle Repair after Ischemia-Reperfusion Injury in Mice 