Titin-Isoform Dependence of Titin-Actin Interaction and Its Regulation by S100A1/Ca²⁺ in Skinned Myocardium

Figure 2

Measurements of titin-based passive tension, before and after gelsolin treatment. (a)–(c) In MLV, BLV, and BLA titin-based passive tension is reduced following gelsolin treatment. At a SL of 2.25 𝜇m. Decrease in titin-based passive tension is largest in MLV, smallest in BLA, with BLV being intermediate. Data are based on Figure 1; see text for details. Error bars are SE (for clarity plotted only every 0.05 𝜇m).

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