Biomolecular Interaction Study of Cyclolinopeptide A with Human Serum Albumin

Table 1

CLP-A/HSA equilibrium binding constants determined from SPR sensorgrams.

Temperature (°C)	𝐾𝑎 (a) (M^−1)	𝐾𝑑 (b) (𝜇M)	𝜒^2
20	757 (33)	1321	4.5
25	1687 (20)	593	1.9
30	7056 (36)	142	1.6
37	50032 (1792)	20	10.2

(a)determined from curve-fitting dose-response curves (Figure 3) with (1). The standard error from curve-fitting are given in brackets.
^(b)𝐾_𝑑=1/𝐾_𝑎.