Mitochondrial Translation and Beyond: Processes Implicated in Combined Oxidative Phosphorylation Deficiencies

Figure 2

Diagram of human mitochondrial protein synthesis. The three phases of mitochondrial translation—initiation, elongation and termination—and all translation factors involved are represented in this figure. See Section 3.2 in the text for a detailed description of all steps (numbered in boxes) of the mitochondrial translation process. Initiation, elongation and termination factors are represented by green, purple and red ovals, respectively. GTP and GDP are shown in yellow and beige circles, respectively.