A New MAP Kinase Protein Involved in Estradiol-Stimulated Reproduction of the Helminth Parasite Taenia crassiceps
Figure 1
Concentration-response and response-time curves. 17-estradiol augments the number of buds in Taenia crassiceps under physiologic concentrations (0.1 M). Specific inhibition of ERK blocks the 17-estradiol effect on the parasite, resulting in a similar number of buds between control and ERK inhibitor-treated cysticerci; (a) 17-estradiol effect was progressively increasing during the five days of in vitro culture, whereas ERK inhibitor 0.5 M did not modify parasite reproduction when compared to control cysticerci, even in presence of 17-estradiol 0.1 M, and (b) Control Parasites treated with the vehicle where hormone and inhibitors were dissolved; .
