Effects of Sizes and Conformations of Fish-Scale Collagen Peptides on Facial Skin Qualities and Transdermal Penetration Efficiency
Figure 4
Size distribution of FSCPs. (a) Fish scale hydrolysates were separated by gel chromatography (superdex peptide 10/300 GL columns); molecular sizes were determined for each fraction; size distributions were plotted accordingly. The size distribution (KDa) is expressed as means SEM. (b) Size profiles of FSCPs. Protein standards (Bio-Rad, California, USA) are cytochrome C (Mr 12500 Da), aprotinin (Mr 6512 Da), vitamin B12 (Mr 1355 Da), and cytidine (Mr 246 Da). The average molecular weights (MWs) were determined to be 4500, 3500, 2000, and 1300 Da for the four indicated groups.