Effects of Sizes and Conformations of Fish-Scale Collagen Peptides on Facial Skin Qualities and Transdermal Penetration Efficiency
Figure 6
Peptide conformations of various sizes of FITC-labeled FSCPs in nude mice skins. Nude mice skins were treated with various molecular sizes of FITC-labeled FSCPs in the Franz-type diffusion cell model. The topical sites of tested nude mice skins were collected in one hour. The vertical cross-sections of the nude mice skins were imaged for FITC signals using cryosection and confocal spectral microscope systems. (a) 1,300 Da FSCPs; (b) 2,000 Da FSCPs; (c) 3,500 Da FSCPs; (d) 4,500 Da FSCPs; and (e) the mixture FSCPs (FSCPs without ultracentrifugation membrane treatment).
