Research Article

Reduction of Foxp Cells by Depletion with the PC61 mAb Induces Mortality in Resistant BALB/c Mice Infected with Toxoplasma gondii

Figure 7

Infection with T. gondii induces an imbalance in Tact: Tregs cell ratio and is exacerbated by depletion. (a) Ratio of Tact: Tregs (CD4+CD25+Foxp3- cells : CD4+Foxp3+ cells) was calculated from data obtained from Figure 6. (b) An additional group of mice ( 𝑛 = 5 ) treated with isotype (white-bullet) or PC61 (black-bullet) was used to evaluate cumulative mortality for 30 days.
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(a)
786078.fig.007b
(b)