BioMed Research International / 2010 / Article / Tab 3

Research Article

Gene Expression Profiling of Placentas Affected by Pre-Eclampsia

Table 3

Regulation of genes in pre-eclamptic placentas compared to controls.

Accession1Gene of interestFold change 𝑃 -value

Antioxidant enzymes
NM_003330.1thioredoxin reductase 1 1 . 5 7 . 0 2 5

Eicosanoid metabolism
U63296.1hydroxyprostaglandin dehydrogenase 15-(NAD+), 1 . 4 8 .027
BC005939.1prostaglandin D2 synthase 21 kDa (brain) 1 . 5 1 . 0 3 1

Energy metabolism
AI761561hexokinase 2 1 . 5 9 . 0 4 5
NM_000230.1leptin 2 . 9 4 . 0 2 5
AA502643tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein e 1 . 6 5 . 0 0 5

Inhibin-activin system
NM_002192.1inhibin, beta A subunit (activin A, activin AB alpha polypeptide) 2 . 0 6 . 0 0 7

Matrix proteins
NM_000494.1collagen, type XVII, alpha 1 1 . 5 0 . 0 3 9
NM_006487.1fibulin 1A 2 . 4 9 . 0 0 9

Transcription factors
AA972711zinc finger protein 292 1 . 3 7 . 0 2 4
NM_005121.1thyroid hormone receptor-associated protein, 240 kDa subunit 1 . 3 2 . 0 1 2

Vascular factors
NM_000710.1bradykinin B1 receptor 1 . 4 4 . 0 2 4
NM_013332.1hypoxia-inducible protein 2 1 . 6 1 . 0 2 9

Miscellaneous
AI206718ESTs, Weakly similar to zinc finger protein 339 1 . 5 2 . 0 2 4
AF052169.1hypothetical protein BC013764 1 . 4 6 . 0 3 3
AF007149.1hypothetical protein LOC257407 1 . 4 0 . 0 3 5
AK025495.1KIAA0790 protein 1 . 5 6 . 0 4 1
AK027231.1KIAA1102 protein 1 . 5 4 . 0 0 3
AB033025.1KIAA1199 protein 1 . 5 9 . 0 4 0
NM_004844.1SH3-domain binding protein 5 (BTK-associated), (signal transduction) 1 . 5 8 . 0 3 0
AF016535.1ATP-binding cassette, sub-family B (MDR/TAP), member 1, (transporter activity) 1 . 4 5 . 0 3 7

1Genbank accession number.