Research Article

Diclofenac-Induced Apoptosis in the Neuroblastoma Cell Line SH-SY5Y: Possible Involvement of the Mitochondrial Superoxide Dismutase

Figure 1

Diclofenac-induced apoptosis in SHSY-5Y cells. (a) SH-SY5Y cells were incubated with the indicated concentrations of diclofenac and apoptosis was evaluated after a 24-hour drug treatment. (b) SH-SY5Y cells were treated with vehicle alone (white bars) or 150 μM diclofenac (black bars) and apoptosis was evaluated after the indicated incubation times. The percentage of apoptosis was measured as described in Section 2.4; * 𝑃 < . 0 1 compared to untreated cells.
801726.fig.001a
(a)
801726.fig.001b
(b)