Diclofenac-Induced Apoptosis in the Neuroblastoma Cell Line SH-SY5Y: Possible Involvement of the Mitochondrial Superoxide Dismutase
Figure 8
Reduction of the mitochondrial membrane potential in the presence of diclofenac. SH-SY5Y cells were incubated with vehicle alone (white bars) or 150 M diclofenac (black bars) for the indicated times. Mitochondrial membrane potential was evaluated through the incorporation of the fluorescent probe R123 as described in Section 2.7. * and #, compared to untreated cells.