Research Article

Diclofenac-Induced Apoptosis in the Neuroblastoma Cell Line SH-SY5Y: Possible Involvement of the Mitochondrial Superoxide Dismutase

Figure 8

Reduction of the mitochondrial membrane potential in the presence of diclofenac. SH-SY5Y cells were incubated with vehicle alone (white bars) or 150  𝜇 M diclofenac (black bars) for the indicated times. Mitochondrial membrane potential was evaluated through the incorporation of the fluorescent probe R123 as described in Section 2.7. * 𝑃 < . 0 1 and # 𝑃 < . 0 5 , compared to untreated cells.
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